Pharmaco-informatics: more precise drug therapy from "multiple model" (MM) stochastic adaptive control regimens: evaluation with simulated vancomycin therapy.

MM stochastic control of dosage regimens permits essentially full use of information, either in a population pharmacokinetic model or a Bayesian updated MM parameter set, to achieve and maintain selected therapeutic goals with optimal precision. The regimens are visibly more precise than those devel...

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Hlavní autoři: Jelliffe, R. W., Bayard, D., Schumitzky, A., Milman, M., Van Guilder, M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Informatics Association 1994
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247806/
https://ncbi.nlm.nih.gov/pubmed/7950076
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