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Polymerase recognition of synthetic oligodeoxyribonucleotides incorporating degenerate pyrimidine and purine bases

A universal base that is capable of substituting for any of the four natural bases in DNA would be of great utility in both mutagenesis and recombinant DNA experiments. This paper describes the properties of oligonucleotides incorporating two degenerate bases, the pyrimidine base 6H,8H-3,4-dihydropy...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hill, F., Loakes, D., Brown, D. M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539724/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4258
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