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Polymerase recognition of synthetic oligodeoxyribonucleotides incorporating degenerate pyrimidine and purine bases

A universal base that is capable of substituting for any of the four natural bases in DNA would be of great utility in both mutagenesis and recombinant DNA experiments. This paper describes the properties of oligonucleotides incorporating two degenerate bases, the pyrimidine base 6H,8H-3,4-dihydropy...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Hill, F., Loakes, D., Brown, D. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1998
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539724/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4258
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