A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides

Although nucleic acid polymerases from different families show striking similarities in structure, they maintain stringent specificity for the sugar structure of the incoming nucleoside triphosphate. The Klenow fragment of E. coli DNA polymerase I selects its natural substrates, deoxynucleotides, ov...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Astatke, Mekbib, Ng, Kimmie, Grindley, Nigel D. F., Joyce, Catherine M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19848/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520378/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3402
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