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The carboxy-terminal coiled-coil of the RNA polymerase β′-subunit is the main binding site for Gre factors
Bacterial Gre transcript cleavage factors stimulate the intrinsic endonucleolytic activity of RNA polymerase (RNAP) to rescue stalled transcription complexes. They bind to RNAP and extend their coiled-coil (CC) domains to the catalytic centre through the secondary channel. Three existing models for...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2247394/ https://ncbi.nlm.nih.gov/pubmed/17917675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401079 |
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