The carboxy-terminal coiled-coil of the RNA polymerase β′-subunit is the main binding site for Gre factors

Bacterial Gre transcript cleavage factors stimulate the intrinsic endonucleolytic activity of RNA polymerase (RNAP) to rescue stalled transcription complexes. They bind to RNAP and extend their coiled-coil (CC) domains to the catalytic centre through the secondary channel. Three existing models for...

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Hlavní autoři: Vassylyeva, Marina N, Svetlov, Vladimir, Dearborn, Altaira D, Klyuyev, Sergiy, Artsimovitch, Irina, Vassylyev, Dmitry G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
Scientific Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247394/
https://ncbi.nlm.nih.gov/pubmed/17917675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401079
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