Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg

Sex comb on midleg (Scm) is a member of the Polycomb group of proteins involved in the maintenance of repression of Hox and other developmental control genes in Drosophila. The two malignant brain tumour (MBT) repeats of Scm form a domain that preferentially binds to monomethylated lysine residues e...

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Main Authors: Grimm, Clemens, de Ayala Alonso, Andres Gaytan, Rybin, Vladimir, Steuerwald, Ulrich, Ly-Hartig, Nga, Fischle, Wolfgang, Müller, Jürg, Müller, Christoph W
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2007
主題:
Scientific Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247378/
https://ncbi.nlm.nih.gov/pubmed/17932512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401085
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