Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg

Sex comb on midleg (Scm) is a member of the Polycomb group of proteins involved in the maintenance of repression of Hox and other developmental control genes in Drosophila. The two malignant brain tumour (MBT) repeats of Scm form a domain that preferentially binds to monomethylated lysine residues e...

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Main Authors: Grimm, Clemens, de Ayala Alonso, Andres Gaytan, Rybin, Vladimir, Steuerwald, Ulrich, Ly-Hartig, Nga, Fischle, Wolfgang, Müller, Jürg, Müller, Christoph W
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2007
Assuntos:
Scientific Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247378/
https://ncbi.nlm.nih.gov/pubmed/17932512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401085
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