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Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg

Sex comb on midleg (Scm) is a member of the Polycomb group of proteins involved in the maintenance of repression of Hox and other developmental control genes in Drosophila. The two malignant brain tumour (MBT) repeats of Scm form a domain that preferentially binds to monomethylated lysine residues e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grimm, Clemens, de Ayala Alonso, Andres Gaytan, Rybin, Vladimir, Steuerwald, Ulrich, Ly-Hartig, Nga, Fischle, Wolfgang, Müller, Jürg, Müller, Christoph W
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247378/
https://ncbi.nlm.nih.gov/pubmed/17932512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401085
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