Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg

Sex comb on midleg (Scm) is a member of the Polycomb group of proteins involved in the maintenance of repression of Hox and other developmental control genes in Drosophila. The two malignant brain tumour (MBT) repeats of Scm form a domain that preferentially binds to monomethylated lysine residues e...

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Autori principali: Grimm, Clemens, de Ayala Alonso, Andres Gaytan, Rybin, Vladimir, Steuerwald, Ulrich, Ly-Hartig, Nga, Fischle, Wolfgang, Müller, Jürg, Müller, Christoph W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
Soggetti:
Scientific Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247378/
https://ncbi.nlm.nih.gov/pubmed/17932512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401085
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