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Effect of calcium antagonists on the chemosensitivity of two multidrug-resistant human tumour cell lines which do not overexpress P-glycoprotein.

We have examined the ability of eight compounds to enhance adriamycin (ADM) sensitivity of two human tumour cell lines (a small cell lung cancer cell line, NCI-H69, and a fibrosarcoma cell line, HT1080) and their multidrug-resistant variants. The resistant cell lines (H69AR and HT1080/DR4) do not ov...

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Main Authors: Cole, S. P., Downes, H. F., Slovak, M. L.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1989
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246955/
https://ncbi.nlm.nih.gov/pubmed/2569325
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