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A structural basis for the allosteric regulation of non-hydrolysing UDP-GlcNAc 2-epimerases
The non-hydrolysing bacterial UDP-N-acetylglucosamine 2-epimerase (UDP-GlcNAc 2-epimerase) catalyses the conversion of UDP-GlcNAc into UDP-N-acetylmannosamine, an intermediate in the biosynthesis of several cell-surface polysaccharides. This enzyme is allosterically regulated by its substrate UDP-Gl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2246411/ https://ncbi.nlm.nih.gov/pubmed/18188181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401154 |
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