A BAC clone fingerprinting approach to the detection of human genome rearrangements

We present a method, called fingerprint profiling (FPP), that uses restriction digest fingerprints of bacterial artificial chromosome clones to detect and classify rearrangements in the human genome. The approach uses alignment of experimental fingerprint patterns to in silico digests of the sequenc...

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Detalhes bibliográficos
Principais autores: Krzywinski, Martin, Bosdet, Ian, Mathewson, Carrie, Wye, Natasja, Brebner, Jay, Chiu, Readman, Corbett, Richard, Field, Matthew, Lee, Darlene, Pugh, Trevor, Volik, Stas, Siddiqui, Asim, Jones, Steven, Schein, Jacquie, Collins, Collin, Marra, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246298/
https://ncbi.nlm.nih.gov/pubmed/17953769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-10-r224
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