Platelet-derived exosomes from septic shock patients induce myocardial dysfunction

INTRODUCTION: Mechanisms underlying inotropic failure in septic shock are incompletely understood. We previously identified the presence of exosomes in the plasma of septic shock patients. These exosomes are released mainly by platelets, produce superoxide, and induce apoptosis in vascular cells by...

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Bibliografiske detaljer
Main Authors: Azevedo, Luciano Cesar Pontes, Janiszewski, Mariano, Pontieri, Vera, Pedro, Marcelo de Almeida, Bassi, Estevão, Tucci, Paulo José Ferreira, Laurindo, Francisco Rafael Martins
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246209/
https://ncbi.nlm.nih.gov/pubmed/17996049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc6176
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