Platelet-derived exosomes from septic shock patients induce myocardial dysfunction

INTRODUCTION: Mechanisms underlying inotropic failure in septic shock are incompletely understood. We previously identified the presence of exosomes in the plasma of septic shock patients. These exosomes are released mainly by platelets, produce superoxide, and induce apoptosis in vascular cells by...

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Autores principales: Azevedo, Luciano Cesar Pontes, Janiszewski, Mariano, Pontieri, Vera, Pedro, Marcelo de Almeida, Bassi, Estevão, Tucci, Paulo José Ferreira, Laurindo, Francisco Rafael Martins
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246209/
https://ncbi.nlm.nih.gov/pubmed/17996049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc6176
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