Platelet-derived exosomes from septic shock patients induce myocardial dysfunction

INTRODUCTION: Mechanisms underlying inotropic failure in septic shock are incompletely understood. We previously identified the presence of exosomes in the plasma of septic shock patients. These exosomes are released mainly by platelets, produce superoxide, and induce apoptosis in vascular cells by...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Azevedo, Luciano Cesar Pontes, Janiszewski, Mariano, Pontieri, Vera, Pedro, Marcelo de Almeida, Bassi, Estevão, Tucci, Paulo José Ferreira, Laurindo, Francisco Rafael Martins
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246209/
https://ncbi.nlm.nih.gov/pubmed/17996049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc6176
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