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Multiple paxillin binding sites regulate FAK function
BACKGROUND: FAK localization to focal adhesions is essential for its activation and function. Localization of FAK is mediated through the C-terminal focal adhesion targeting (FAT) domain. Recent structural analyses have revealed two paxillin-binding sites in the FAT domain of FAK. To define the role...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2246129/ https://ncbi.nlm.nih.gov/pubmed/18171471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-3-1 |
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