Cross-Correlated Fluctuation Analysis Reveals Phosphorylation-Regulated Paxillin-FAK Complexes in Nascent Adhesions

We used correlation methods to detect and quantify interactions between paxillin and focal adhesion kinase (FAK) in migrating cells. Cross-correlation raster-scan image correlation spectroscopy revealed that wild-type paxillin and the phosphorylation-inhibiting paxillin mutant Y31F-Y118F do not inte...

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Main Authors: Choi, Colin K., Zareno, Jessica, Digman, Michelle A., Gratton, Enrico, Horwitz, Alan Rick
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2011
Teme:
Cellular Biophysics and Electrophysiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030238/
https://ncbi.nlm.nih.gov/pubmed/21281572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.12.3719
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