The androgen receptor can signal through Wnt/β-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens

BACKGROUND: A crucial event in Prostate Cancer progression is the conversion from a hormone-sensitive to a hormone-refractory disease state. Correlating with this transition, androgen receptor (AR) amplification and mutations are often observed in patients failing hormonal ablation therapies. β-Cate...

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Autors principals: Schweizer, Liang, Rizzo, Cheryl A, Spires, Thomas E, Platero, J Suso, Wu, Qiuyan, Lin, Tai-An, Gottardis, Marco M, Attar, Ricardo M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246119/
https://ncbi.nlm.nih.gov/pubmed/18218096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-9-4
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