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Preventing DNA over-replication: a Cdk perspective

The cell cycle is tightly controlled to ensure that replication origins fire only once per cycle and that consecutive S-phases are separated by mitosis. When controls fail, DNA over-replication ensues: individual origins fire more than once per S-phase (re-replication) or consecutive S-phases occur...

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Detalles Bibliográficos
Autor Principal: Porter, Andrew CG
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2245919/
https://ncbi.nlm.nih.gov/pubmed/18211690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-3-3
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