Parameters Driving the Selection of Nelfinavir-Resistant Human Immunodeficiency Virus Type 1 Variants
We investigated the parameters driving nelfinavir resistance, along the D30N and L90M evolutionary pathways. The advantage of the D30N mutant was mostly due to its resistance level, while the L90M mutation allowed preservation of infectivity coupled with minimal resistance. Emergence of secondary mu...
שמור ב:
| הוצא לאור ב: | J Virol |
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| Principais autores: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
2003
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC224578/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12941931/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.18.10172-10175.2003 |
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