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Parameters Driving the Selection of Nelfinavir-Resistant Human Immunodeficiency Virus Type 1 Variants

We investigated the parameters driving nelfinavir resistance, along the D30N and L90M evolutionary pathways. The advantage of the D30N mutant was mostly due to its resistance level, while the L90M mutation allowed preservation of infectivity coupled with minimal resistance. Emergence of secondary mu...

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Bibliográfalaš dieđut
Publikašuvnnas:J Virol
Váldodahkkit: Perrin, Virginie, Mammano, Fabrizio
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: American Society for Microbiology (ASM) 2003
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC224578/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12941931/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.18.10172-10175.2003
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