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The E3 ubiquitin ligase skp2 regulates neural differentiation independent from the cell cycle

BACKGROUND: The SCF(skp2 )complex is an E3 ubiquitin ligase that is known to target a number of cell cycle regulators, including cyclin-dependent kinase inhibitors, for proteolysis. While its role in regulation of cell division has been well documented, additional functions in differentiation, inclu...

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Hlavní autoři: Boix-Perales, Hector, Horan, Ian, Wise, Helen, Lin, Horng-Ru, Chuang, Li-Chiou, Yew, P Renee, Philpott, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2244796/
https://ncbi.nlm.nih.gov/pubmed/18081928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-2-27
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