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Calcium block of Na(+) channels and its effect on closing rate

Calcium ion transiently blocks Na(+) channels, and it shortens the time course for closing of their activation gates. We examined the relation between block and closing kinetics by using the Na(+) channels natively expressed in GH3 cells, a clonal line of rat pituitary cells. To simplify analysis, i...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Armstrong, C. M., Cota, Gabriel
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22436/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097179/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.4154
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