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An Immortalized Human Cell Line Bearing a PRKAR1A-Inactivating Mutation: Effects of Overexpression of the Wild-Type Allele and Other Protein Kinase A Subunits
Context: Inactivating mutations of PRKAR1A, the regulatory subunit type 1A (RIα) of protein kinase A (PKA), are associated with tumor formation. Objective: Our objective was to evaluate the role of PKA isozymes on proliferation and cell cycle. Methods: A cell line with RIα haploinsufficiency due to...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2243228/ https://ncbi.nlm.nih.gov/pubmed/18056771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2007-1902 |
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