Partial Inhibition of Sarcoplasmic Reticulum Ca Release Evokes Long-Lasting Ca Release Events in Ventricular Myocytes: Role of Luminal Ca in Termination of Ca Release()

In cardiac myocytes, local sarcoplasmic reticulum (SR) Ca depletion during Ca sparks is believed to play an important role in the termination of SR Ca release. We tested whether decreasing the rate of SR Ca depletion by partially inhibiting SR Ca release channels (ryanodine receptors) delays Ca spar...

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Detalhes bibliográficos
Main Authors: Zima, Aleksey V., Picht, Eckard, Bers, Donald M., Blatter, Lothar A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Cell Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242770/
https://ncbi.nlm.nih.gov/pubmed/18024505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.114694
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