Effect of Metabolic Inhibition on Couplon Behavior in Rabbit Ventricular Myocytes()()

We investigated the effect of combined inhibition of oxidative and glycolytic metabolism on L-type Ca(2+) channels (LCCs) and Ca(2+) spikes in isolated patch-clamped rabbit ventricular myocytes. Metabolic inhibition (MI) reduced LCC open probability, increased null probability, increased first laten...

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Hauptverfasser: Chantawansri, Chana, Huynh, Nhi, Yamanaka, Jun, Garfinkel, Alan, Lamp, Scott T., Inoue, Masashi, Bridge, John H.B., Goldhaber, Joshua I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2008
Schlagworte:
Channels, Receptors, and Electrical Signaling
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242765/
https://ncbi.nlm.nih.gov/pubmed/18024504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.114892
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