Na(+) currents are required for efficient excitation–contraction coupling in rabbit ventricular myocytes: a possible contribution of neuronal Na(+) channels

Ca(2+) transients were activated in rabbit ventricular cells by a sequence of action potential shaped voltage clamps. After activating a series of control transients, Na(+) currents (I(Na)) were inactivated with a ramp from −80 to −40 mV (1.5 s) prior to the action potential clamp. The transients we...

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Main Authors: Torres, Natalia S, Larbig, Robert, Rock, Alex, Goldhaber, Joshua I, Bridge, John H B
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2010
Ábhair:
Cardiovascular
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002454/
https://ncbi.nlm.nih.gov/pubmed/20837647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.194688
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