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Excitation-contraction coupling in single guinea-pig ventricular myocytes exposed to hydrogen peroxide.

1. The effects of hydrogen peroxide (H2O2), an in vitro free radical generating system, on excitation-contraction (E-C) coupling were studied in isolated adult guinea-pig ventricular myocytes using Ca(2+)-sensitive dyes and the patch-clamp technique. 2. In paced myocytes loaded with indo-1 AM, 1 mM...

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Bibliographic Details
Main Authors: Goldhaber, J I, Liu, E
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1155581/
https://ncbi.nlm.nih.gov/pubmed/8071880
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