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Mechanisms of excitation-contraction coupling failure during metabolic inhibition in guinea-pig ventricular myocytes.

1. The effects of complete metabolic inhibition on excitation-contraction coupling in heart were studied by exposing patch-clamped guinea-pig ventricular myocytes, loaded via the patch pipette with the Ca2+ indicator Fura-2 (0.1 mM), to carbonyl cyanide-p-trifluoromethoxyphenylhydrazone (FCCP, 1 mic...

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Detalhes bibliográficos
Main Authors: Goldhaber, J I, Parker, J M, Weiss, J N
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1179846/
https://ncbi.nlm.nih.gov/pubmed/1822531
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