PPARα agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition

Angiogenesis and inflammation are central processes through which the tumor microenvironment influences tumor growth. We have demonstrated recently that peroxisome proliferator-activated receptor (PPAR)α deficiency in the host leads to overt inflammation that suppresses angiogenesis via excess produ...

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Bibliografiske detaljer
Main Authors: Panigrahy, Dipak, Kaipainen, Arja, Huang, Sui, Butterfield, Catherine E., Barnés, Carmen M., Fannon, Michael, Laforme, Andrea M., Chaponis, Deviney M., Folkman, Judah, Kieran, Mark W.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242705/
https://ncbi.nlm.nih.gov/pubmed/18199835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711281105
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