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Manipulating and understanding antibiotic production in Streptomyces coelicolor A3(2) with decoy oligonucleotides

We have adapted and extended the decoy oligonucleotide technique for use in prokaryotes. To identify cis-acting regulatory elements within a promoter, we developed a DNase I/T7 exonuclease footprinting technique and applied it to actII-orf4 from Streptomyces coelicolor A3(2), which encodes the pathw...

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Hlavní autoři: McArthur, Michael, Bibb, Mervyn J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242687/
https://ncbi.nlm.nih.gov/pubmed/18187578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710724105
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