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EshA Accentuates ppGpp Accumulation and Is Conditionally Required for Antibiotic Production in Streptomyces coelicolor A3(2)

Disruption of eshA, which encodes a 52-kDa protein that is produced late during the growth of Streptomyces coelicolor A3(2), resulted in elimination of actinorhodin production. In contrast, disruption of eshB, a close homologue of eshA, had no effect on antibiotic production. The eshA disruptant acc...

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Detalhes bibliográficos
Main Authors: Saito, Natsumi, Xu, Jun, Hosaka, Takeshi, Okamoto, Susumu, Aoki, Hiroyuki, Bibb, Mervyn J., Ochi, Kozo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483009/
https://ncbi.nlm.nih.gov/pubmed/16788203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00343-06
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