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Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages
Phagocytes generate nitric oxide (NO) and other reactive oxygen and nitrogen species in large quantities to combat infecting bacteria. Here, we report the surprising observation that in vivo survival of a notorious pathogen—Bacillus anthracis—critically depends on its own NO-synthase (bNOS) activity...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242674/ https://ncbi.nlm.nih.gov/pubmed/18215992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710950105 |
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