Bacterial Nitric-oxide Synthases Operate without a Dedicated Redox Partner

Bacterial nitric-oxide (NO) synthases (bNOSs) are smaller than their mammalian counterparts. They lack an essential reductase domain that supplies electrons during NO biosynthesis. This and other structural peculiarities have raised doubts about whether bNOSs were capable of producing NO in vivo. He...

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Detalhes bibliográficos
Main Authors: Gusarov, Ivan, Starodubtseva, Marina, Wang, Zhi-Qiang, McQuade, Lindsey, Lippard, Stephen J., Stuehr, Dennis J., Nudler, Evgeny
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Enzyme Catalysis and Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442334/
https://ncbi.nlm.nih.gov/pubmed/18316370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710178200
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