Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: Reverse docking, enzymatic assay, and X-ray crystallography validation

Colonization of human stomach by the bacterium Helicobacter pylori is a major causative factor for gastrointestinal illnesses and gastric cancer. However, the discovery of anti-H. pylori agents is a difficult task due to lack of mature protein targets. Therefore, identifying new molecular targets fo...

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Hlavní autoři: Cai, Jianhua, Han, Cong, Hu, Tiancen, Zhang, Jian, Wu, Dalei, Wang, Fangdao, Liu, Yunqing, Ding, Jianping, Chen, Kaixian, Yue, Jianmin, Shen, Xu, Jiang, Hualiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242601/
https://ncbi.nlm.nih.gov/pubmed/16882991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062238406
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