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Mutagenic exploration of the cross-seeding and fibrillation propensity of Alzheimer's β-amyloid peptide variants

Amyloid formation is a nucleation-dependent process that is accelerated dramatically in vivo and in vitro upon addition of appropriate fibril seeds. A potent species barrier can be effective in this reaction if donor and recipient come from different biological species. This species barrier is thoug...

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Détails bibliographiques
Auteurs principaux: Peim, Alexander, Hortschansky, Peter, Christopeit, Tony, Schroeckh, Volker, Richter, Walter, Fändrich, Marcus
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242566/
https://ncbi.nlm.nih.gov/pubmed/16751608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062116206
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