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Modular organization of FDH: Exploring the basis of hydrolase catalysis

An abundant enzyme of liver cytosol, 10-formyltetrahydrofolate dehydrogenase (FDH), is an interesting example of a multidomain protein. It consists of two functionally unrelated domains, an aldehyde dehydrogenase-homologous domain and a folate-binding hydrolase domain, which are connected by an ~100...

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Autors principals: Reuland, Steven N., Vlasov, Alexander P., Krupenko, Sergey A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242502/
https://ncbi.nlm.nih.gov/pubmed/16597835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.052062806
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