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Modular organization of FDH: Exploring the basis of hydrolase catalysis
An abundant enzyme of liver cytosol, 10-formyltetrahydrofolate dehydrogenase (FDH), is an interesting example of a multidomain protein. It consists of two functionally unrelated domains, an aldehyde dehydrogenase-homologous domain and a folate-binding hydrolase domain, which are connected by an ~100...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242502/ https://ncbi.nlm.nih.gov/pubmed/16597835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.052062806 |
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