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Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1

Expression of the DMP1 transcription factor, a cyclin D-binding Myb-like protein, induces growth arrest in mouse embryo fibroblast strains but is devoid of antiproliferative activity in primary diploid fibroblasts that lack the ARF tumor suppressor gene. DMP1 binds to a single canonical recognition...

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Bibliographic Details
Main Authors: Inoue, Kazushi, Roussel, Martine F., Sherr, Charles J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC22408/
https://ncbi.nlm.nih.gov/pubmed/10097151
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