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Rapid-Equilibrium Rate Equations for the Enzymatic Catalysis of A + B = P + Q over a Range of pH†

This article shows how pKs for the enzymatic site and enzyme-substrate complexes can be obtained from kinetic experiments on the reaction A + B = P + Q, with and without the consumption of hydrogen ions. The rapid-equilibrium rate equation makes it possible to obtain the pKs and chemical equilibrium...

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Autor principal: Alberty, Robert A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2239239/
https://ncbi.nlm.nih.gov/pubmed/18061334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2007.10.015
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