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Efficient and accurate P-value computation for Position Weight Matrices

BACKGROUND: Position Weight Matrices (PWMs) are probabilistic representations of signals in sequences. They are widely used to model approximate patterns in DNA or in protein sequences. The usage of PWMs needs as a prerequisite to knowing the statistical significance of a word according to its score...

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Bibliografiske detaljer
Main Authors: Touzet, Hélène, Varré, Jean-Stéphane
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238751/
https://ncbi.nlm.nih.gov/pubmed/18072973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-2-15
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