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Efficient and accurate P-value computation for Position Weight Matrices

BACKGROUND: Position Weight Matrices (PWMs) are probabilistic representations of signals in sequences. They are widely used to model approximate patterns in DNA or in protein sequences. The usage of PWMs needs as a prerequisite to knowing the statistical significance of a word according to its score...

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Bibliografske podrobnosti
Main Authors: Touzet, Hélène, Varré, Jean-Stéphane
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238751/
https://ncbi.nlm.nih.gov/pubmed/18072973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-2-15
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