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Engineering and Characterization of a Mouse/Human Chimeric Anti-Phencyclidine Monoclonal Antibody

Previously, our laboratory produced a high affinity, anti-phencyclidine (PCP) murine monoclonal antibody (mAb6B5) that also binds other PCP-like arylcyclohexylamines. In this project, mAb6B5 is engineered into a mouse/human chimera (ch-mAb6B5) to assess the feasibility of developing it into a medica...

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Bibliografische gegevens
Hoofdauteurs: Lacy, H. Marie, Gunnell, Melinda G., Laurenzana, Elizabeth M., Owens, S. Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238695/
https://ncbi.nlm.nih.gov/pubmed/18068094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2007.09.020
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