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Engineering and Characterization of a Mouse/Human Chimeric Anti-Phencyclidine Monoclonal Antibody
Previously, our laboratory produced a high affinity, anti-phencyclidine (PCP) murine monoclonal antibody (mAb6B5) that also binds other PCP-like arylcyclohexylamines. In this project, mAb6B5 is engineered into a mouse/human chimera (ch-mAb6B5) to assess the feasibility of developing it into a medica...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2238695/ https://ncbi.nlm.nih.gov/pubmed/18068094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2007.09.020 |
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