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NOVEL IDENTIFICATION OF UDP-GLUCURONOSYLTRANSFERASE 1A10 AS AN ESTROGEN REGULATED TARGET GENE
Recently, we have shown that UGT1A10 is actively involved in the inactivation of E(1), E(2), and their 2- and 4-hydroxylated derivatives. In the present study, we show for the first time that treatment of the MCF-7 ER-positive breast cancer cell line with E(2) produces a dose-dependent up-regulation...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2238686/ https://ncbi.nlm.nih.gov/pubmed/17981312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2007.09.007 |
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