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NOVEL IDENTIFICATION OF UDP-GLUCURONOSYLTRANSFERASE 1A10 AS AN ESTROGEN REGULATED TARGET GENE

Recently, we have shown that UGT1A10 is actively involved in the inactivation of E(1), E(2), and their 2- and 4-hydroxylated derivatives. In the present study, we show for the first time that treatment of the MCF-7 ER-positive breast cancer cell line with E(2) produces a dose-dependent up-regulation...

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Detaylı Bibliyografya
Asıl Yazarlar: Starlard-Davenport, Athena, Lyn-Cook, Beverly, Radominska-Pandya, Anna
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238686/
https://ncbi.nlm.nih.gov/pubmed/17981312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2007.09.007
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