Influence of ligand structure on Fe(II) spin-state and redox rate in cytotoxic tripodal chelators

The Fe coordination chemistry of several tripodal aminopyridyl hexadentate chelators is reported along with cytotoxicity toward cultured Hela cells. The chelators are based on cis, cis-1,3,5-triaminocyclohexane (tach) with three pendant –CH(2)–2-pyridyl groups where 2-pyridyl is R-substituted thus a...

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Bibliografiske detaljer
Main Authors: Childers, Matt L., Cho, Joonhyung, Regino, Celeste A. S., Brechbiel, Martin W., DiPasquale, Antonio G., Rheingold, Arnold L., Torti, Suzy V., Torti, Frank M., Planalp, Roy P.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238680/
https://ncbi.nlm.nih.gov/pubmed/17900698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2007.07.039
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