Cargando...

Evolution of the pregnane X receptor: adaptation to cross-species differences in biliary bile salts

The pregnane X receptor (PXR) regulates the metabolism and elimination of bile salts, steroids, and xenobiotics. The sequence of the PXR ligand-binding domain diverges extensively between different animals suggesting inter-species differences in ligands. Of the endogenous ligands known to activate P...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Krasowski, Matthew D., Yasuda, Kazuto, Hagey, Lee R., Schuetz, Erin G.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238640/
https://ncbi.nlm.nih.gov/pubmed/15718292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2004-0427
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!