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Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation

Metallothionein-I (MT-I) gene is silenced by methylation of CpG islands in mouse lymphosarcoma P1798 cells but not in the thymus, the cell type from which the tumor was derived. Bisulfite genomic sequencing revealed that all 21 CpG dinucleotides present within −216 bp to +1 bp with respect to transc...

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Autores principales: Majumder, Sarmila, Ghoshal, Kalpana, Li, Zhiling, Bo, Yuan, Jacob, Samson T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2237891/
https://ncbi.nlm.nih.gov/pubmed/10597227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1203004
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