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Suppression of metallothionein-I/II expression and its probable molecular mechanisms.

Metallothionein (MT) promoter was methylated in rat hepatoma and in mouse lymphosarcoma cells by methylation of cytosine within the CpG dinucleotide region. After demethylation of MT-I promoter in mouse lymphosarcoma cells or in the transplanted rat hepatoma with 5-azacytidine, a potent inhibitor of...

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Main Authors: Jacob, Samson T, Majumder, Sarmila, Ghoshal, Kalpana
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1241254/
https://ncbi.nlm.nih.gov/pubmed/12426140
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