T-Cell Receptor Gene Therapy of Established Tumors in a Murine Melanoma Model

Adoptive cell transfer therapy using tumor-infiltrating lymphocytes for patients with metastatic melanoma has demonstrated significant objective response rates. One major limitation of these current therapies is the frequent inability to isolate tumor-reactive lymphocytes for treatment. Genetic engi...

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Bibliographic Details
Main Authors:	Abad, John D., Wrzensinski, Claudia, Overwijk, Willem, De Witte, Moniek A., Jorritsma, Annelies, Hsu, Gary, Gattinoni, Luca, Cohen, Cyrille J., Paulos, Chrystal M., Palmer, Douglas C., Haanen, John B. A. G., Schumacher, Ton N. M., Rosenberg, Steven A., Restifo, Nicholas P., Morgan, Richard A.
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2235937/ https://ncbi.nlm.nih.gov/pubmed/18157006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31815c193f
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T-Cell Receptor Gene Therapy of Established Tumors in a Murine Melanoma Model

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