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Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia

BACKGROUND: Activated microglia elicits a robust amount of pro-inflammatory cytokines, which are implicated in the pathogenesis of tuberculosis in the central nervous system (CNS). However, little is known about the intracellular signaling mechanisms governing these inflammatory responses in microgl...

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Detalhes bibliográficos
Main Authors: Yang, Chul-Su, Lee, Hye-Mi, Lee, Ji-Yeon, Kim, Jeong-Ah, Lee, Sung Joong, Shin, Dong-Min, Lee, Young-Ho, Lee, Dong-Seok, El-Benna, Jamel, Jo, Eun-Kyeong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2235845/
https://ncbi.nlm.nih.gov/pubmed/18036262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-4-27
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